Ruchinskaia T Iu, Sverdlov Iu S, Serbeniuk Ts V
Zh Evol Biokhim Fiziol. 1976 Jul-Aug;12(4):314-21.
Spontaneous rhythmic impulse discharges of motoneurons of spinal centers of the posterior lymphatic hearts have been recorded from the ventral roots of isolated spinal cord perfused by oxygenated Ringer's solution. Inhibition of the transmission in interneuronal synapses evoked by abolition of Ca ions from the external solution and by the addition to the latter of 1--4 mM EDTA was accompanied by the block of the spontaneous impulse activity. Blocking of rhythmic efferent discharges in the anterior roots was also observed after the addition to normal Ringer's solution of 10--30 mM MgCl2. Inhibition of the spontaneous activity by high Mg content in the perfusion fluid could be alleviated by the addition of 5--15 mM CaCl2 to this solution. Antidromic impulses in the ventral roots of the XI and X segments, evoked by rhythmic electrical stimulation of these roots, did not affect the intrinsic rhythm of motor discharges.
从用含氧林格氏液灌注的离体脊髓腹根记录到后淋巴心脊髓中枢运动神经元的自发性节律性冲动发放。当从外部溶液中去除钙离子并向其中加入1-4 mM乙二胺四乙酸（EDTA），从而抑制中间神经元突触传递时，会伴随着自发冲动活动的阻断。在正常林格氏液中加入10-30 mM氯化镁后，也观察到前根节律性传出放电的阻断。通过向灌注液中加入5-15 mM氯化钙，可以缓解灌注液中高镁含量对自发活动的抑制作用。通过对第十一和第十节段腹根进行节律性电刺激所诱发的逆行冲动，并不影响运动放电的固有节律。
