Földes I, Nagy Z, Petkó M
Acta Biol Acad Sci Hung. 1975;26(3-4):141-50.
Comparative spectroscopic investigations were performed on 22 trace elements regarding their presence and quantitative relations in cartilages (costal cartilage, intervertebral disc) and in soft tissues most exposed to metastatic calcification (aorta, kidney) of normal, vitamin D2-treated and rachitic rats. The results revealed differences in concentration and distribution of trace elements between soft tissues and cartilages on the one hand, and untreated controls and vitamin D-treated rats on the other. On vitamin D treatment an increase in the Cr, Fe and Cu contents was noted in the soft tissues, whereas in cartilages a higher Zn content was shown. It is suggested that these trace elements may play an important role in the mechanism of calcification, some acting as challengers, others as adjuvants or inhibitors.
对22种微量元素在正常、经维生素D2处理和患佝偻病的大鼠的软骨（肋软骨、椎间盘）以及最易发生转移性钙化的软组织（主动脉、肾脏）中的存在情况和定量关系进行了比较光谱研究。结果显示，一方面软组织和软骨之间，另一方面未处理的对照组和经维生素D处理的大鼠之间，微量元素的浓度和分布存在差异。经维生素D处理后，软组织中的铬、铁和铜含量增加，而软骨中锌含量较高。有人认为，这些微量元素可能在钙化机制中起重要作用，一些作为激发因素，另一些作为辅助因素或抑制因素。
