Salvesen R, Hugaas K A
Nevrologisk avdeling, Nordland Sentralsykehus, Bodø.
Tidsskr Nor Laegeforen. 2000 Apr 30;120(11):1304-6.
Patients known to harbour a cerebral arteriovenous malformation that is inaccessible to therapy may have a second bleeding into the subarachnoid space, but from another source.
Two patients had previously bled from an intracranial arteriovenous malformation; both were considered inaccessible to surgical or endovascular repair. The patients were then admitted to hospital with symptoms and signs suggesting a second subarachnoid haemorrhage.
Diagnostic work-up demonstrated an aneurysm as the probable source of haemorrhage in both patients.
Patients harbouring an intracranial arteriovenous malformation are much more likely to develop an associated intracranial aneurysm than patients without such malformations, and a second bleeding in these patients will more often arise from the associated aneurysm. The cause of the frequent association of an aneurysm is probably haemodynamic stress due to the increased blood flow through the feeding artery. These patients suffer subarachnoid haemorrhage more often than patients with either an aneurysm or a malformation alone. The therapeutic strategy should be carefully individualized and the aneurysm should more often have priority.
已知患有无法进行治疗的脑动静脉畸形的患者可能会再次发生蛛网膜下腔出血,但出血来源不同。
两名患者曾因颅内动静脉畸形出血;两人均被认为无法进行手术或血管内修复。随后,这两名患者因出现提示再次蛛网膜下腔出血的症状和体征而入院。
诊断检查表明,两名患者出血的可能来源均为动脉瘤。
患有颅内动静脉畸形的患者比没有此类畸形的患者更易发生相关的颅内动脉瘤,这些患者的再次出血更常源于相关动脉瘤。动脉瘤频繁关联的原因可能是由于通过供血动脉的血流量增加导致的血流动力学压力。这些患者比单独患有动脉瘤或畸形的患者更常发生蛛网膜下腔出血。治疗策略应谨慎个体化,动脉瘤通常应优先处理。