[Mastocytosis--a review illustrated by two case reports].
作者信息
Dalgaard J, Ritland S, Brinch L, Ikonomou I M
机构信息
Medisinsk avdeling Buskerud Sentralsykehus, Drammen.
出版信息
Tidsskr Nor Laegeforen. 2000 Apr 30;120(11):1312-5.
BACKGROUND
Mastocytosis includes a range of disorders characterised by accumulation of tissue mast cells. These are derived from pluripotent haematopoietic stem cells. Recent research has improved the understanding of the mastocytosis pathogenesis. Organ manifestations and symptoms are highly variable.
MATERIAL AND METHODS
Two cases of systemic mast cell disease are presented.
RESULTS
One patient had urticaria pigmentosa and systemic mast cell disease; the other had systemic mast cell disease and myelodysplastic changes in the bone marrow.
INTERPRETATION
The two cases illustrate different manifestations and different prognosis for various types of mastocytosis.
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