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Evidence that the different properties of haloperidol and clozapine are not explained by differences in anticholinergic potency.

作者信息

Ljungberg T, Ungerstedt U

出版信息

Psychopharmacology (Berl). 1979 Feb 28;60(3):303-7. doi: 10.1007/BF00426672.

DOI:10.1007/BF00426672
PMID:108708
Abstract
摘要

相似文献

1
Evidence that the different properties of haloperidol and clozapine are not explained by differences in anticholinergic potency.氟哌啶醇和氯氮平的不同特性并非由抗胆碱能效力的差异所解释的证据。
Psychopharmacology (Berl). 1979 Feb 28;60(3):303-7. doi: 10.1007/BF00426672.
2
Behavioral evidence for supersensitivity after chronic administration of haloperidol, clozapine, and thioridazine.长期服用氟哌啶醇、氯氮平和硫利达嗪后超敏反应的行为学证据。
Life Sci. 1976 Sep 1;19(5):725-31. doi: 10.1016/0024-3205(76)90170-3.
3
Blockade of lergotrile or apomorphine induced turning behavior by haloperidol and clozapine.氟哌啶醇和氯氮平对麦角腈或阿扑吗啡诱导的旋转行为的阻断作用。
Commun Psychopharmacol. 1978;2(3):185-90.
4
Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: studies with chronic clozapine and haloperidol.抗精神病药物所致多巴胺能超敏反应的行为学和生物化学方面：慢性氯氮平和氟哌啶醇研究
Psychopharmacology (Berl). 1982;76(2):182-7. doi: 10.1007/BF00435275.
5
Differential sensitivity to amphetamine following long-term treatment with clozapine or haloperidol.长期使用氯氮平或氟哌啶醇治疗后对苯丙胺的敏感性差异
Psychopharmacology (Berl). 1982;77(4):360-6. doi: 10.1007/BF00432771.
6
Detection of the nueroleptic properties of clozapine, sulpiride and thioridazine.氯氮平、舒必利和硫利达嗪的抗精神病特性检测。 你提供的原文中“nueroleptic”拼写有误，正确的是“neuroleptic” 。
Psychopharmacologia. 1975 Jul 23;43(1):69-74. doi: 10.1007/BF00437617.
7
[Effects of anticholinergics and clozapine on the activation of the striatal dopaminergic system in the rat by haloperidol. Pharmacological findings (author's transl)].[抗胆碱能药物和氯氮平对氟哌啶醇激活大鼠纹状体多巴胺能系统的影响。药理学研究结果（作者译）]
Arzneimittelforschung. 1976;26(6):1092-3.
8
In vivo actions of clozapine and haloperidol on the turnover rate of acetylcholine in rat striatum.氯氮平和氟哌啶醇对大鼠纹状体中乙酰胆碱周转率的体内作用。
J Pharmacol Exp Ther. 1976 Feb;196(2):323-32.
9
The effects of haloperidol and clozapine on circling induced by electrical stimulation of the substantia nigra and the ventromedial tegmentum.氟哌啶醇和氯氮平对电刺激黑质和腹内侧被盖区诱导的转圈行为的影响。
Neuropharmacology. 1978 Nov;17(11):943-6. doi: 10.1016/0028-3908(78)90136-3.
10
Apomorphine provoked stereotype in the dog.阿扑吗啡可诱发犬的刻板行为。
Psychopharmacologia. 1972;26(4):361-8. doi: 10.1007/BF00421901.

引用本文的文献

1
Similarity of clozapine's and olanzapine's acute effects on rats' lapping behavior.氯氮平和奥氮平对大鼠舔舐行为急性影响的相似性。
Psychopharmacology (Berl). 1996 Feb;123(4):374-8. doi: 10.1007/BF02246648.
2
Acute and subchronic effects of clozapine on licking in rats: tolerance to disruptive effects on number of licks, but no tolerance to rhythm slowing.氯氮平对大鼠舔舐行为的急性和亚慢性影响：对舔舐次数的干扰效应产生耐受性，但对节奏减慢无耐受性。
Psychopharmacology (Berl). 1995 Aug;120(3):249-55. doi: 10.1007/BF02311171.
3
Unlike haloperidol, clozapine slows and dampens rats' forelimb force oscillations and decreases force output in a press-while-licking behavioral task.

本文引用的文献

1
Influence of antiparkinson drugs and amphetamine on some pharmacological effects of phenothiazine derivatives used as neuroleptics.抗帕金森病药物和苯丙胺对用作抗精神病药的吩噻嗪衍生物某些药理作用的影响。
Psychopharmacologia. 1964 Sep 11;6(3):178-91. doi: 10.1007/BF00404008.
2
Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats.阿扑吗啡和右旋苯丙胺对大鼠啃咬强迫行为的作用机制
Psychopharmacologia. 1967;10(4):316-23. doi: 10.1007/BF00403900.
3
The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine (clozapine).
Psychopharmacology (Berl). 1994 Sep;116(1):19-25. doi: 10.1007/BF02244866.
4
Differential effects of haloperidol and clozapine on attention.氟哌啶醇和氯氮平对注意力的不同影响。
Psychopharmacology (Berl). 1984;84(2):268-73. doi: 10.1007/BF00427457.
5
Antipsychotic drug effects on the behavior of squirrel monkeys differentially controlled by noxious stimuli.抗精神病药物对松鼠猴行为的影响，这些行为受有害刺激的不同控制。
Psychopharmacology (Berl). 1982;77(1):1-6. doi: 10.1007/BF00436091.
6
Effects of fluperlapine on dopaminergic systems in rat brain.氟哌拉平对大鼠脑内多巴胺能系统的影响。
Psychopharmacology (Berl). 1986;89(1):77-84. doi: 10.1007/BF00175194.
7
Blockade of acquisition of one-way conditioned avoidance responding by haloperidol and metoclopramide but not by thioridazine or clozapine: implications for screening new antipsychotic drugs.氟哌啶醇和胃复安可阻断单向条件性回避反应的习得，但硫利达嗪或氯氮平则不然：这对筛选新型抗精神病药物具有启示意义。
Psychopharmacology (Berl). 1989;98(4):453-9. doi: 10.1007/BF00441941.
8
Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: evidence for two different mechanisms of action.根据神经安定药物抑制阿扑吗啡诱导的运动和啃咬能力进行的分类：两种不同作用机制的证据。
Psychopharmacology (Berl). 1978 Apr 11;56(3):239-47. doi: 10.1007/BF00432845.
8-氯-11-（4-甲基-1-哌嗪基）-5H-二苯并[b,e][1,4]二氮杂卓（氯氮平）的药理学
Farmaco Prat. 1971 Oct;26(10):603-25.
4
The role of telencephalic dopaminergic systems in the mediation of apomorphine-stereotyped behaviour.端脑多巴胺能系统在阿扑吗啡刻板行为介导中的作用。
Eur J Pharmacol. 1973 Oct;24(1):8-24. doi: 10.1016/0014-2999(73)90108-8.
5
Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?抗精神病药物的作用：精神分裂症神经病理学的线索？
Fed Proc. 1973 Feb;32(2):200-5.
6
Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects.
J Psychiatr Res. 1974;11:91-5. doi: 10.1016/0022-3956(74)90078-8.
7
Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism.
Nature. 1974 Apr 12;248(449):596-7. doi: 10.1038/248596a0.
8
Clozapine and the dopamine hypothesis of schizophrenia, a critical appraisal.氯氮平与精神分裂症的多巴胺假说：一项批判性评估
Pharmakopsychiatr Neuropsychopharmakol. 1975 May;8(3):115-21. doi: 10.1055/s-0028-1094449.
9
Differential attenuation of some effects of haloperidol in rats given scopolamine.东莨菪碱处理大鼠中氟哌啶醇某些效应的差异衰减
Eur J Pharmacol. 1976 Sep;39(1):117-26. doi: 10.1016/0014-2999(76)90119-9.
10
Different behavioural patterns induced by apomorphine: evidence that the method of administration determines the behavioural response to the drug.阿扑吗啡诱导的不同行为模式：给药方式决定药物行为反应的证据。
Eur J Pharmacol. 1977 Nov 1;46(1):41-50. doi: 10.1016/0014-2999(77)90142-x.