Verdolini R, Goteri G, Brancorsini D, Collina G, Simonetti O, Offidani A, Giangiacomi M
Department of Dermatology, University of Ancona, Italy.
Am J Dermatopathol. 2000 Jun;22(3):264-7. doi: 10.1097/00000372-200006000-00011.
We describe two cases of adult rhabdomyoma. One was located in the lip of a 66-year-old woman and was removed because it was clinically suspicious for infiltrating carcinoma. The other arose in the eyelid of a 60-year-old woman with a glass eye and was initially interpreted as a reactive process due to the prosthesis. Both lesions were composed of cells with oval nuclei and deeply eosinophilic cytoplasms with occasional cross striations. Immunoreactivity for desmin and myoglobin excluded the diagnosis of other tumors with similar morphology. The unusual association of the eyelid tumor with the prosthesis suggests a role for chronic irritation in the pathogenesis of rhabdomyoma.
我们描述了两例成人横纹肌瘤。一例位于一名66岁女性的唇部，因临床怀疑为浸润性癌而被切除。另一例发生在一名60岁装有玻璃义眼的女性的眼睑，最初因假体被解释为一种反应性过程。两个病变均由具有椭圆形核和深嗜酸性细胞质且偶尔有横纹的细胞组成。结蛋白和肌红蛋白的免疫反应性排除了其他形态学相似肿瘤的诊断。眼睑肿瘤与假体的异常关联提示慢性刺激在横纹肌瘤发病机制中起作用。
