肺挫伤的精细结构及各种药物的作用。

Casley-Smith J R, Eckert P, Földi-Börcsök E

Br J Exp Pathol. 1976 Oct;57(5):487-96.

The results of contusion were examined by electron and light microscopy in the lungs of rats. It was found that the results here were very similar to those elsewhere in the body, with a few minor modifications due to the unique structure of the lung. Densitometry of protein concentration and visual estimation of oedema were used to quantitate the effects on the injury. The benzo-pyrone drug Venalot had a considerable effect in reducing the protein concentration in the air spaces and the interstitial tissue, and of the oedema in the latter. Neither the proteinase inhibitor Trasylol nor the pectin-based plasma expander HAS had any significant effect on the fine structural alterations of pulmonary contusion.

通过电子显微镜和光学显微镜对大鼠肺部挫伤结果进行了检查。发现此处的结果与身体其他部位非常相似，只是由于肺的独特结构而有一些微小的差异。使用蛋白质浓度光密度测定法和水肿的视觉评估来量化对损伤的影响。苯并吡喃类药物维纳洛在降低肺泡腔和间质组织中的蛋白质浓度以及后者的水肿方面有显著效果。蛋白酶抑制剂抑肽酶和基于果胶的血浆扩容剂HAS对肺挫伤的细微结构改变均无显著影响。