Tahlan A, Nijhawan R, Joshi K
Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Anal Quant Cytol Histol. 2000 Jun;22(3):193-8.
To investigate the relevance of image analysis for grading breast carcinoma.
Twenty-five ductal breast carcinoma cases were chosen randomly from routine fine needle aspiration clinics. The results of cytomorphologic grading and image morphometry were correlated with those of histologic grading. The five image morphometric parameters studied were nuclear diameter, nuclear area, nuclear roundness, nuclear perimeter and grey level to compare with chromatin texture.
Cytologic grading alone had a high correlation with histologic grading. The lowest correlation was found in grade 2 tumors. When cytologic grading was supplemented with image morphometric parameters, the correlation was higher than that of cytologic grading alone.
Cytologic grading has a high correlation with histologic grading. The correlation improves further on supplementation with image morphometric parameters.
探讨图像分析在乳腺癌分级中的相关性。
从常规细针穿刺诊所随机选取25例乳腺导管癌病例。将细胞形态学分级和图像形态计量学结果与组织学分级结果进行相关性分析。所研究的五个图像形态计量学参数为核直径、核面积、核圆度、核周长和灰度水平，以与染色质纹理进行比较。
单独的细胞学分级与组织学分级具有高度相关性。在2级肿瘤中相关性最低。当细胞学分级辅以图像形态计量学参数时，相关性高于单独的细胞学分级。
细胞学分级与组织学分级具有高度相关性。补充图像形态计量学参数后相关性进一步提高。
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