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[免疫功能低下患者的巨细胞病毒病]

[Cytomegalovirus disease in immunocompromised patients].

作者信息

Zvizdić S, Beslagić E, Kapić E, Zvizdić-Karahodzić M

机构信息

Medicinski fakultet Univerziteta u Sarajevu.

出版信息

Med Arh. 2000;54(1):9-11.

Abstract

Human Cytomegalovirus are a ubiquitous herpesvirus establishing virus-infections which are usually asymptomatic in immunocompetent individuals. In patients with Acquired Immunodeficiency Syndrome (AIDS) and immunocompromised hosts, the virus causes primary, latent or chronic persistent infection. Primary CMV infection is very severe in immunocompromised patients as well as among healthy population. Among patients with AIDS Cytomegalovirus (CMV) is usually isolated from patients specimen in association with other pathogens (Pneumocystis carinii, Candida albicans). The prevalence of serious CMV (chorioretinitis, gastrointestinal disease, interstitial pneumonia and central nervous system disease), in AIDS population are respectable.

摘要

人巨细胞病毒是一种普遍存在的疱疹病毒,可引发病毒感染,在免疫功能正常的个体中通常无症状。在获得性免疫缺陷综合征(艾滋病)患者和免疫功能低下的宿主中,该病毒会导致原发性、潜伏性或慢性持续性感染。原发性巨细胞病毒感染在免疫功能低下的患者以及健康人群中都非常严重。在艾滋病患者中,巨细胞病毒(CMV)通常与其他病原体(卡氏肺孢子虫、白色念珠菌)一起从患者标本中分离出来。艾滋病患者中严重巨细胞病毒感染(脉络膜视网膜炎、胃肠道疾病、间质性肺炎和中枢神经系统疾病)的患病率相当高。

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