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[在一个随机临床样本中,结核菌素试验与内镜图像比较中的结节病活动情况]

[Sarcoidosis activity in a comparison of the tuberculin test and the endoscopic picture in a randomized clinical sample].

作者信息

Mehić B, Dizdarević Z

机构信息

Klinika za plućne bolesti tuberkulozu Podhrastovi, Klinicki centar Univerziteta u Sarajevu.

出版信息

Med Arh. 2000;54(1):45-8.

Abstract

The study population consisted of 100 patients with sarcoidosis, selected by method of accidental selection. According to clinical form of sarcoidosis, the sample was divided, in three groups: group of patients with chronic form of sarcoidosis (SHFS)--36 patients, group of patients with acute form of sarcoidosis (SAFS)--46 patients, and group of patients with asymptomatic form of sarcoidosis (SAsFS)--18 patients. The aim of study was to determine whether there were statistically significant differences between the groups of different sarcoidosis clinical forms in diagnosis time in connection with tuberculin reaction, endoscopic picture and index of sarcoidosis activity? Which level of correlation was between index of sarcoidosis activity and tuberculin reaction, respectively endoscopic picture on observed groups of sarcoidosis patients? On the basis of our results we reached the following conclusions: there was significant correlation between magnitude of tuberculin reaction and index of sarcoidosis activity in SAsFS, in SAFS correlation there was no significance and in SHFS there was no correlation. In all of three groups the most frequent was endoscopic picture of enlarged and irregularly arranged capillaries with yellowish plaques on bronchial mucous with average index of activity (6.7).

摘要

研究人群由100例结节病患者组成,采用随机抽样法选取。根据结节病的临床类型,样本被分为三组:慢性结节病组(SHFS)——36例患者,急性结节病组(SAFS)——46例患者,无症状结节病组(SAsFS)——18例患者。研究目的是确定不同结节病临床类型组在诊断时间上与结核菌素反应、内镜图像及结节病活动指数之间是否存在统计学显著差异?结节病活动指数与结核菌素反应以及观察到的结节病患者组的内镜图像之间的相关程度如何?基于我们的结果,我们得出以下结论:在无症状结节病组中,结核菌素反应强度与结节病活动指数之间存在显著相关性,在急性结节病组中相关性不显著,在慢性结节病组中无相关性。在所有三组中,最常见的内镜图像是支气管黏膜上毛细血管扩张且排列不规则,伴有淡黄色斑块,平均活动指数为(6.7)。

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