Kurkchubasche A G, Halvorson E G, Forman E N, Terek R M, Ferguson W S
Department of Surgery, Rhode Island Hospital and Brown University School of Medicine, Providence, USA.
J Pediatr Surg. 2000 Jun;35(6):880-3. doi: 10.1053/jpsu.2000.6871.
Infantile fibrosarcoma (IFS) is a rare tumor most often affecting the extremities of infants and young children. Unlike its adult counterpart, IFS has a low potential for metastatic spread, and surgical extirpation alone has therefore resulted in an excellent prognosis. The amputation rate, however, exceeds 50%. The dramatic response in 2 recent cases to preoperative chemotherapy, given in an attempt to avoid amputation, prompted this report and a review of the literature.
婴儿纤维肉瘤(IFS)是一种罕见肿瘤,最常累及婴幼儿的四肢。与成人纤维肉瘤不同,IFS发生转移扩散的可能性较低,因此仅通过手术切除就能带来良好的预后。然而,截肢率超过50%。最近有2例患者为避免截肢而接受术前化疗,化疗效果显著,促使撰写本报告并对文献进行回顾。