Seino K, Tanji S, Yamamoto T, Fujizuka I, Ohinata M, Kubo T, Ohhori T
Department of Urology, School of Medicine, Iwate Medical University.
Hinyokika Kiyo. 1987 Nov;33(11):1906-12.
Rhabdomyosarcoma of the prostate is a rare tumor and its prognosis is extremely poor. However, the survival rate has been gradually improved by using combined chemotherapy. A 17-year-old man with the chief complaint of dysuria was referred to our hospital on April 7, 1986. Prostatic needle biopsy was performed and pathological diagnosis was rhabdomyosarcoma of the prostate. The patient was given preoperative combined chemotherapy consisting of actinomycin D and cyclophosphamide. Total cystoprostaurethrectomy and ileal conduit were performed on April 30, 1986. He underwent postoperative combined chemotherapy (vincristine, actinomycin D, cyclophosphamide). He is well 13 months after his initial symptoms and is clinically free of tumor 12 months postoperatively. Forty-two cases of rhabdomyosarcoma of the prostate including our case were collected from the Japanese literature and reviewed with respect to the multimodal treatment and prognosis.
前列腺横纹肌肉瘤是一种罕见肿瘤,其预后极差。然而,通过联合化疗,生存率已逐渐提高。一名17岁男性因排尿困难为主诉于1986年4月7日转诊至我院。进行了前列腺穿刺活检,病理诊断为前列腺横纹肌肉瘤。患者接受了由放线菌素D和环磷酰胺组成的术前联合化疗。1986年4月30日进行了全膀胱前列腺尿道切除术及回肠代膀胱术。他术后接受了联合化疗(长春新碱、放线菌素D、环磷酰胺)。自出现初始症状起13个月后他情况良好,术后12个月临床未见肿瘤。从日本文献中收集了包括我们病例在内的42例前列腺横纹肌肉瘤病例,并就多模式治疗和预后进行了回顾。