Miller M, Hemenway D, Bell N S, Yore M M, Amoroso P J
Department of Health Policy and Management, Harvard University School of Public Health, Boston, MA, USA.
Am J Epidemiol. 2000 Jun 1;151(11):1060-3. doi: 10.1093/oxfordjournals.aje.a010148.
The authors examined the relation between cigarette smoking and suicide by conducting a cohort study of 300,000 male US Army personnel followed prospectively from January 1987 through December 1996 for 961,657 person-years. They found that the risk of suicide increased significantly with the number of cigarettes smoked daily (p for trend < 0.001). In multivariable-adjusted analyses, smokers of more than 20 cigarettes a day, compared with never smokers, were more than twice as likely to commit suicide. For male active-duty army personnel, the dose-related association between smoking and suicide was not entirely explained by the greater tendency of smokers to be White, drink heavily, have less education, and exercise less often.
作者通过对30万名美国陆军男性人员进行队列研究，前瞻性地追踪了从1987年1月至1996年12月共961,657人年，研究了吸烟与自杀之间的关系。他们发现，自杀风险随每日吸烟量的增加而显著增加（趋势p值<0.001）。在多变量调整分析中，每天吸烟超过20支的吸烟者与从不吸烟者相比，自杀的可能性是后者的两倍多。对于现役陆军男性人员，吸烟与自杀之间的剂量相关关联并不能完全由吸烟者更倾向于为白人、酗酒、受教育程度较低和运动频率较低来解释。
