Brown D A
Department of Pharmacology, University College London, UK.
Curr Biol. 2000 Jun 15;10(12):R456-9. doi: 10.1016/s0960-9822(00)00532-7.
The K(+) channels that generate the resting potential of mammalian neurons have been difficult to identify and characterize. Recent experiments on hypoglossal motoneurons and cerebellar granule cells suggest that the resting current in these neurons is carried by TASK-1, a member of the twin-pore family of K(+) channels.
产生哺乳动物神经元静息电位的钾离子通道一直难以识别和表征。最近对舌下运动神经元和小脑颗粒细胞的实验表明,这些神经元中的静息电流是由TASK-1携带的,TASK-1是钾离子通道双孔家族的一员。