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恶性黑色素瘤中的异常前哨淋巴结

Aberrant sentinel nodes in malignant melanoma.

作者信息

O'Toole G A, Hettiaratchy S, Allan R, Powell B W

机构信息

Department of Plastic and Reconstructive Surgery, St George's Hospital, London, UK.

出版信息

Br J Plast Surg. 2000 Jul;53(5):415-7. doi: 10.1054/bjps.1999.3309.

DOI:10.1054/bjps.1999.3309
PMID:10876280
Abstract

The option of sentinel lymph node biopsy for patients with a cutaneous malignant melanoma has allowed an alternative to the traditional approaches to lymph node basin surgery. Lymphatic mapping usually identifies the sentinel node(s) in a recognised lymphatic basin, however aberrant nodes may occasionally be identified outside these areas. The notes of 100 consecutive patients with a localised cutaneous malignant melanoma, who had a sentinel lymph node biopsy in our unit, were reviewed. Lymphatic mapping identified three patients with aberrant sentinel lymph nodes. Failure to remove an aberrant sentinel lymph node harbouring metastatic melanoma may reduce significantly the chance of control or cure of the disease. In order to reduce this risk we advocate lymphatic mapping prior to surgical management of the draining lymph nodes of a cutaneous malignant melanoma.

摘要

对于皮肤恶性黑色素瘤患者,前哨淋巴结活检为淋巴结清扫术的传统方法提供了一种替代方案。淋巴绘图通常可识别出公认淋巴区域内的前哨淋巴结,但偶尔也可能在这些区域外发现异常淋巴结。我们回顾了在我院接受前哨淋巴结活检的100例连续性局限性皮肤恶性黑色素瘤患者的病历。淋巴绘图发现3例患者存在异常前哨淋巴结。未能切除存在转移性黑色素瘤的异常前哨淋巴结可能会显著降低疾病得到控制或治愈的几率。为降低这种风险,我们提倡在对皮肤恶性黑色素瘤的引流淋巴结进行手术治疗前进行淋巴绘图。

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Aberrant sentinel nodes in malignant melanoma.恶性黑色素瘤中的异常前哨淋巴结
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引用本文的文献

1
Surgical management of tumor-positive interval node in melanoma patients: An observational study.黑色素瘤患者肿瘤阳性间期淋巴结的外科治疗:一项观察性研究。
Medicine (Baltimore). 2018 May;97(18):e0584. doi: 10.1097/MD.0000000000010584.
2
Interval sentinel lymph nodes in melanoma: a digital pathology analysis of Ki67 expression and microvascular density.黑色素瘤中的间隔前哨淋巴结:Ki67表达和微血管密度的数字病理学分析
Clin Exp Med. 2016 Aug;16(3):383-9. doi: 10.1007/s10238-015-0379-9. Epub 2015 Aug 15.
3
Functional anatomy of the lymphatics draining the skin: a detailed statistical analysis.
引流皮肤的淋巴管的功能解剖:详细的统计分析。
J Anat. 2010 Mar;216(3):344-55. doi: 10.1111/j.1469-7580.2009.01183.x. Epub 2010 Jan 7.