[人类、大猩猩、黑猩猩和红毛猩猩之间的关系]

[The relationship among human, gorilla, chimpanzee and orangutan].

作者信息

Ding B, Zhang Y P, Ryder O A

机构信息

Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences.

出版信息

Yi Chuan Xue Bao. 1999;26(6):604-9.

PMID:10876659

Abstract

The phylogeny of hominoid is still an open question. The contrary point is which relationship is more closed related between human and gorilla and human and chimpanzee. Tyrosinase is the essential enzyme in melanogenesis. The mutation of tyrosinase gene causes albinism. The five exons of tyrosinase gene were sequenced for gorilla, chimpanzee, orangutan and gibbon in hominoid. Combined with the human tyrosinase gene sequence, the gene tree was constructed using parsimony method. The results show that the relationship between human and gorilla is more closed related than between human and chimpanzee.

摘要

类人猿的系统发育仍然是一个悬而未决的问题。相反的观点是，人类与大猩猩以及人类与黑猩猩之间哪种关系更为密切。酪氨酸酶是黑色素生成中的关键酶。酪氨酸酶基因突变会导致白化病。对类人猿中的大猩猩、黑猩猩、猩猩和长臂猿的酪氨酸酶基因的五个外显子进行了测序。结合人类酪氨酸酶基因序列，采用简约法构建了基因树。结果表明，人类与大猩猩的关系比人类与黑猩猩的关系更为密切。