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[在健康中心接受护理的2型糖尿病患者的慢性并发症]

[Chronic complications in patients with type 2 diabetes mellitus cared for at a health center].

作者信息

Zafra Mezcua J A, Méndez Segovia J C, Novalbos Ruiz J P, Costa Alonso M J, Faílde Martínez I

机构信息

Servicio de Medicina Preventiva, Hospital Universitario de Puerto Real, Cádiz.

出版信息

Aten Primaria. 2000 May 15;25(8):529-35. doi: 10.1016/s0212-6567(00)78562-3.

Abstract

OBJECTIVE

To know the chronic complications affecting a type-2 diabetic population in a health center, and to analyze the relationship between these complications and risk factors.

DESIGN

Transversal study.

SETTING

Puerto de Santa Maria-Norte Health Center, Cadiz, Spain.

PATIENTS

Type-2 diabetic population (n = 504) included in the diabetes program of the center, aged over 12 years old, of both sexes.

MEASUREMENTS AND MAIN RESULTS

The prevalence of type 2 diabetes recorded was 2.3%. Average age of the population was 63.9 years (SD 10.6), women representing 57.9% of total. Average length of evolution of the disease was 8.6 years (SD 11.4). 17.1% of patients were receiving insulin therapy, 65.4% were receiving oral antidiabetics, and 17.5% were on special diet. The most important risk factors found were: family history of diabetes (54.6%), obesity (51.2%), sedentary life style (41.1%), and hypertension (47.2%). Chronic complications affected 67.8% of the diabetic patients attending the center; predominant complications were peripheral vascular disease (31.7%), retinopathy (30.6%), ischemic heart disease (21.2%), cerebrovascular accident (10.7%), neuropathy (8.9%) and nephropathy (6.2%). The risk factors most associated with macrovascular complications were: length of evolution, smoking and age of diagnostic and hypertriglyceridemia. For the microvascular complications were: HbA1c, length of evolution and age.

CONCLUSIONS

We found a significative prevalence of complications in spite of the average length of disease evolution time in the population not being very high. However the risk factors strongest associated with the existence of chronic complications are susceptible to be modified with a better metabolic control of the patients.

摘要

目的

了解某健康中心2型糖尿病患者群体的慢性并发症情况,并分析这些并发症与危险因素之间的关系。

设计

横断面研究。

地点

西班牙加的斯圣玛丽亚 - 诺特港健康中心。

患者

纳入该中心糖尿病项目的2型糖尿病患者群体(n = 504),年龄超过12岁,男女不限。

测量指标及主要结果

记录的2型糖尿病患病率为2.3%。该群体的平均年龄为63.9岁(标准差10.6),女性占总数的57.9%。疾病的平均病程为8.6年(标准差11.4)。17.1%的患者接受胰岛素治疗,65.4%接受口服降糖药治疗,17.5%采用特殊饮食。发现的最重要危险因素为:糖尿病家族史(54.6%)、肥胖(51.2%)、久坐生活方式(41.1%)和高血压(47.2%)。慢性并发症影响了该中心67.8%的糖尿病患者;主要并发症为外周血管疾病(31.7%)、视网膜病变(30.6%)、缺血性心脏病(21.2%)、脑血管意外(10.7%)、神经病变(8.9%)和肾病(6.2%)。与大血管并发症最相关的危险因素为:病程、吸烟、诊断时年龄和高甘油三酯血症。与微血管并发症相关的危险因素为:糖化血红蛋白、病程和年龄。

结论

尽管该群体疾病平均病程不是很长,但我们发现并发症的患病率较高。然而,与慢性并发症存在最密切相关的危险因素可通过对患者更好的代谢控制来加以改善。

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