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IVIAT:一种鉴定人类感染期间特异性表达的微生物基因的新方法。

IVIAT: a novel method to identify microbial genes expressed specifically during human infections.

作者信息

Handfield M, Brady L J, Progulske-Fox A, Hillman J D

机构信息

Center for Molecular Microbiology and Dept of Oral Biology, College of Dentistry, University of Florida, Box 100424 JHMHSC, 1600 SW Archer Rd, Gainesville, FL 32610-0424, USA.

出版信息

Trends Microbiol. 2000 Jul;8(7):336-9. doi: 10.1016/s0966-842x(00)01775-3.

DOI:10.1016/s0966-842x(00)01775-3
PMID:10878769
Abstract

In vivo induced antigen technology (IVIAT) is a novel technology that can quickly and easily identify in vivo induced genes in human infections, without the use of animal models. This technology is expected to facilitate the discovery of new targets for vaccines, antimicrobials and diagnostic strategies in a wide range of microbial pathogens.

摘要

体内诱导抗原技术(IVIAT)是一项新技术,它无需使用动物模型,就能快速且轻松地识别人类感染中的体内诱导基因。这项技术有望推动在多种微生物病原体中发现疫苗、抗菌药物和诊断策略的新靶点。

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