Hocqueloux L, Bruneel F, Pages C L, Vachon F
Clinique de Réanimation des Maladies Infectieuses, Hôpital Bichat-Claude Bernard, 75018 Paris, France.
Clin Infect Dis. 2000 Jun;30(6):940-2. doi: 10.1086/313814.
We report the first 2 cases of fatal invasive aspergillosis complicating severe malaria. In 2 nonimmune European adults without underlying disease, death was directly ascribable to invasive aspergillosis. We believe that transient malaria-induced immunosuppression allowed massive growth and overwhelming dissemination of preexisting Aspergillus colonization.
我们报告了首例2例致命性侵袭性曲霉病并发严重疟疾的病例。在2名无基础疾病的非免疫欧洲成年人中，死亡直接归因于侵袭性曲霉病。我们认为，短暂的疟疾诱导的免疫抑制使得先前存在的曲霉菌定植大量生长并广泛播散。
