Glockner J F, White L M, Sundaram M, McDonald D J
Department of Radiology, St. Louis University Hospital, MO 63110-0250, USA.
Skeletal Radiol. 2000 May;29(5):270-4. doi: 10.1007/s002560050606.
To describe a series of patients with no known primary malignancy who presented with a solitary unsuspected soft tissue metastasis masquerading as a soft tissue sarcoma, and secondarily to describe the imaging appearance of these lesions.
Records of two academic hospitals with active orthopedic oncology services were reviewed for patients meeting the above criteria. Clinical charts were examined, and the imaging appearance of the soft tissue lesions retrospectively reviewed.
Of 1421 patients examined for soft tissue lesions, 11 were found who met the above criteria.
Of the 11 patients whose initial presentation was a solitary soft tissue metastasis, eight were found to have a primary lung cancer, two were diagnosed with adenocarcinoma of unknown primary, and adenocarcinoma of the colon was discovered in the remaining patient.
The clinical presentation of a solitary soft tissue metastasis without a known primary malignancy is a rare occurrence, with an incidence of approximately 0.8%. Lung cancer is the primary neoplasm in a high percentage of these cases.
描述一系列无已知原发性恶性肿瘤的患者，这些患者表现为单个未被怀疑的软组织转移瘤，伪装成软组织肉瘤，其次描述这些病变的影像学表现。
回顾了两家设有活跃骨肿瘤服务的学术医院中符合上述标准的患者记录。检查临床病历，并回顾性分析软组织病变的影像学表现。
在1421例接受软组织病变检查的患者中，发现11例符合上述标准。
在最初表现为单个软组织转移瘤的11例患者中，8例被发现患有原发性肺癌，2例被诊断为原发性不明的腺癌，其余1例患者被发现患有结肠癌。
无已知原发性恶性肿瘤的单个软组织转移瘤的临床表现罕见，发生率约为0.8%。在这些病例中，肺癌是主要的肿瘤类型。
