Sakorafas G H, Tsiotou A G
Department of Surgery, 251 Hellenic Air Force (HAF) Hospital, Missogion and Katchaki, Athens, Greece.
Surg Oncol. 1999 Jul;8(1):27-33. doi: 10.1016/s0960-7404(99)00016-x.
Patients with occult breast cancer pose a challenging diagnostic and therapeutic problem. High-quality mammography is required to decrease the false-negative rates. A number of other imaging methods have been proposed in the diagnostic evaluation of these women, including breast ultrasonography, color Doppler ultrasonography, breast magnetic resonance imaging (MRI), positron emission tomography (PET), and scintimammography. Among them, MRI may be particularly helpful, since it has a high sensitivity and may enable preoperative localization of the primary, thus allowing the surgeon to perform a breast conserving procedure. Treatment options include surgery, radiotherapy and watchful waiting (followed by mastectomy when a breast tumor is detected). Systemic therapy is usually required in the management of these patients.
隐匿性乳腺癌患者带来了具有挑战性的诊断和治疗问题。需要高质量的乳腺钼靶检查以降低假阴性率。在对这些女性进行诊断评估时，已经提出了许多其他成像方法，包括乳腺超声检查、彩色多普勒超声检查、乳腺磁共振成像（MRI）、正电子发射断层扫描（PET）和乳腺闪烁显像。其中，MRI可能特别有用，因为它具有高灵敏度，并且可以在术前对原发灶进行定位，从而使外科医生能够实施保乳手术。治疗选择包括手术、放疗和观察等待（当检测到乳腺肿瘤时随后进行乳房切除术）。这些患者的管理通常需要全身治疗。
