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大网膜胸廓内移位术作为纵隔炎治疗辅助手段的随机研究利弊分析

Thoracic transposition of the greater omentum as an adjunct in the treatment of mediastinitis--pros and cons within the context of a randomised study.

作者信息

Krabatsch T, Schmitt D V, Mohr F W, Hetzer R

机构信息

Dept. of Cardio-thoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany.

出版信息

Eur J Surg Suppl. 1999(584):45-8. doi: 10.1080/11024159950188547.

DOI:10.1080/11024159950188547
PMID:10890232
Abstract

Mediastinitis after cardiac surgery is a rare but life-threatening complication. The omentum is particularly well-suited for the treatment of severe sternal wound infections, because it contains large numbers of immunologically active cells that seem to be responsible for the high anti-infective activity of the omentum. The additional transposition of parts of the greater omentum into the thorax was discussed in the development of a protocol for the planned ATMI study, which will investigate the effectiveness of immunoglobulins in the treatment of severe sternal wound infections that require reoperation. We present two different points of view about whether omentopexy should be allowed within the study design.

摘要

心脏手术后纵隔炎是一种罕见但危及生命的并发症。大网膜特别适合用于治疗严重的胸骨伤口感染,因为它含有大量免疫活性细胞,这些细胞似乎是大网膜具有高抗感染活性的原因。在一项计划中的ATMI研究方案的制定过程中,讨论了将部分大网膜额外转位至胸腔的问题,该研究将调查免疫球蛋白在治疗需要再次手术的严重胸骨伤口感染中的有效性。对于在研究设计中是否应允许进行大网膜固定术,我们提出了两种不同的观点。

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Thoracic transposition of the greater omentum as an adjunct in the treatment of mediastinitis--pros and cons within the context of a randomised study.大网膜胸廓内移位术作为纵隔炎治疗辅助手段的随机研究利弊分析
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