McCowan C, Marik P
Department of Emergency Medicine, University of Massachusetts Medical Center, Worcester, USA.
Crit Care Med. 2000 Jun;28(6):1781-4. doi: 10.1097/00003246-200006000-00014.
Delirium tremens, the most serious manifestation of alcohol withdrawal, occurs in approximately 5% of hospitalized alcoholics and has a mortality rate approaching 15%. Patients with delirium tremens are usually treated in an intensive care unit in which benzodiazepines form the cornerstone of therapy. In this report, we describe four patients who proved refractory to high doses of benzodiazepines and were successfully treated with a propofol infusion.
震颤谵妄是酒精戒断最严重的表现形式，约5%的住院酗酒者会出现，死亡率接近15%。震颤谵妄患者通常在重症监护病房接受治疗，其中苯二氮䓬类药物是治疗的基石。在本报告中，我们描述了4例对高剂量苯二氮䓬类药物治疗无效，但通过丙泊酚输注成功治疗的患者。
