Seta N, Arfi C, Momas I
Laboratoire d'Hygiène et de Santé Publique, UFR des Sciences Pharmaceutiques et Biologiques, 75270 Paris. Cedex 06, France.
Rev Epidemiol Sante Publique. 2000 Jun;48(3):281-93.
This paper gives an overview of the environmental or background exposure of general population to dioxins, polychlorinated dibenzo-para-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF), originating from a variety of industrial and thermal processes and recognized as cancerous and toxic substances. The daily consumption of low-level contaminated food, mainly of animal origin, leads to the accumulation of dioxins in the human body. To determine the background exposure, human milk, adipose tissue or blood from many geographical locations (except France) have been used as bioindicators for body burden of dioxins. Human milk also allows the daily intake estimation of dioxins for breast-fed babies. Efforts should be made to minimize or avoid PCDD/PCDF emission in the environment.
本文概述了普通人群通过各种工业和热过程接触二噁英、多氯二苯并对二噁英(PCDD)和多氯二苯并呋喃(PCDF)的环境或背景暴露情况,这些物质被公认为致癌和有毒物质。日常食用低水平污染食品(主要是动物性食品)会导致二噁英在人体中蓄积。为确定背景暴露情况,来自许多地理位置(法国除外)的母乳、脂肪组织或血液已被用作二噁英体内负荷的生物指标。母乳还可用于估算母乳喂养婴儿的二噁英每日摄入量。应努力尽量减少或避免环境中PCDD/PCDF的排放。