Ziglar M K
Trauma Outreach, University of North Carolina Hospitals, Chapel Hill, USA.
Int J Trauma Nurs. 2000 Jul-Sep;6(3):81-4. doi: 10.1067/mtn.2000.108033.
Clinical measures, such as blood pressure or urine output, have been the traditional methods used to assess tissue perfusion in trauma patients with hypovolemia. Hypoperfusion of tissues results in increased levels of lactate and carbonic acids. Base deficit is a clinical measure of metabolic acidosis that normalizes rapidly with adequate resuscitation and hemorrhage control, and it can be used to monitor the initial care of a patient with trauma. The method used to measure base deficit is discussed, along with its clinical uses and limitations. A case study is used to correlate changes in base deficit with other clinical parameters.
诸如血压或尿量等临床指标一直是评估低血容量创伤患者组织灌注的传统方法。组织灌注不足会导致乳酸和碳酸水平升高。碱缺失是代谢性酸中毒的一项临床指标，在充分复苏和控制出血后会迅速恢复正常，可用于监测创伤患者的初始治疗情况。本文讨论了测量碱缺失的方法及其临床应用和局限性。通过一个案例研究来关联碱缺失的变化与其他临床参数。
