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中性水溶液中还原型细胞色素c的构象变化

Changes in conformation of reduced cytochrome c in neutral aqueous solution.

作者信息

Land E J, Swallow A J

出版信息

Biochem J. 1976 Sep 1;157(3):781-4. doi: 10.1042/bj1570781.

Abstract

In neutral aqueous solution, high concentrations of alcohols perturb cytochrome c in such a way that reduction by means of ionizing radiation results in the formation of abnormal conformers of ferrocytochrome c resembling those previously seen on reduction in alkaline solution. These relax to normal ferrocytochrome c in about 0.1 s.

摘要

在中性水溶液中,高浓度的醇类会以这样一种方式干扰细胞色素c,即通过电离辐射进行还原会导致亚铁细胞色素c形成异常构象体,类似于先前在碱性溶液中还原时所观察到的构象体。这些构象体在约0.1秒内会松弛恢复为正常的亚铁细胞色素c。

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