Whiteman P J, Hoffman R S, Goldfrank L R
Department of Emergency Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Acad Emerg Med. 2000 Jan;7(1):14-20. doi: 10.1111/j.1553-2712.2000.tb01884.x.
To describe the epidemiology of alcoholism in ED patients.
Over a two-month period, every adult patient brought by ambulance to the ED of a large municipal hospital was prospectively enrolled by questionnaire. Data collected included demographics, previous ED use, triage complaint-related diagnoses, hospital admission rates, and ethanol levels (if determined). The CAGE alcoholism questions were administered to all patients by trained assistants. The only exclusion criterion was the inability to communicate while in the ED. A chi-square analysis was used to compare categorical variables.
A total of 2,658 patients were enrolled in the study; 226 were unable to respond to the CAGE questions. Five hundred eighty-eight of the remaining 2,432 patients (24%) were defined as being alcoholic by an affirmative response to at least two of the CAGE questions. All four questions were answered affirmatively by 17% of the total patients. Alcoholic patients were more likely to be male (88% vs 60%), unemployed (87% vs 71%), undomiciled (46% vs 20%), polysubstance users (52% vs 25%), and tobacco users (77% vs 41%), and to have had an ED visit in the previous six months (51% vs 35%) (p < 0.001 for all tests). Ethanol levels ranged from zero to 573 mg/dL. Whereas no positive response to a single CAGE question was predictive of a final diagnosis of alcoholism, a blood ethanol level more than 300 mg/dL predicted an affirmative response to at least two CAGE questions in 97% of cases.
Alcoholism should be presumed to be present in a substantial number of patients who present to urban EDs by ambulance.
描述急诊科患者酒精中毒的流行病学特征。
在两个月的时间里,通过问卷调查对每一位由救护车送至一家大型市立医院急诊科的成年患者进行前瞻性登记。收集的数据包括人口统计学信息、既往急诊科就诊情况、分诊主诉相关诊断、住院率以及乙醇水平(若已测定)。由经过培训的助手向所有患者询问CAGE酒精中毒问题。唯一的排除标准是在急诊科无法进行交流。采用卡方分析比较分类变量。
共有2658例患者纳入本研究;226例无法回答CAGE问题。在其余2432例患者中,588例(24%)对至少两个CAGE问题回答为肯定,被定义为酒精中毒患者。所有四个问题回答均为肯定的患者占总患者数的17%。酒精中毒患者更可能为男性(88%对60%)、失业者(87%对71%)、无固定住所者(46%对20%)、多种物质使用者(52%对25%)和吸烟者(77%对41%),且在前六个月内有过急诊科就诊经历(51%对35%)(所有检验p<0.001)。乙醇水平范围为0至573mg/dL。虽然对单个CAGE问题的肯定回答不能预测最终的酒精中毒诊断,但血液乙醇水平超过300mg/dL在97%的病例中可预测对至少两个CAGE问题回答为肯定。
对于大量通过救护车送至城市急诊科的患者,应假定存在酒精中毒情况。