Haji S A, Movahed A
Department of Medicine, East Carolina University School of Medicine, Greenville, North Carolina 27858, USA.
Clin Cardiol. 2000 Jul;23(7):473-82. doi: 10.1002/clc.4960230721.
Right ventricular infarction (RVI) as assessed by various diagnostic methods accompanies inferior-posterior wall myocardial infarction (MI) in 30 to 50% of patients. Recognition of the syndrome of RVI is important as it defines a significant clinical entity, which is associated with considerable immediate morbidity and mortality and has a well-delineated set of priorities for its management. Patients may clinically present with hypotension, elevated jugular venous pulse (JVP), and occasionally shock, all in the presence of clear lung fields. The ST-segment elevation of > or = 0.1 mV in the right precordial leads V4R is a readily available electrocardiographic sign used for diagnosis of RVI. Other diagnostic approaches for assessing RVI include echocardiography, radionuclide ventriculography, technetium pyrophosphate scanning, and hemodynamic measurements. The proper management of RVI includes volume loading to maintain adequate right ventricular preload, ionotropic support, and maintenance of atrioventricular synchrony. Reperfusion therapy should be initiated at the earliest signs of right ventricular dysfunction. Finally, complete recovery over a period of weeks to months is a rule in a majority of patients, suggesting right ventricular "stunning" rather than irreversible necrosis has occurred.
通过各种诊断方法评估,右心室梗死(RVI)在30%至50%的患者中与下后壁心肌梗死(MI)同时出现。认识RVI综合征很重要,因为它定义了一个重要的临床实体,与相当高的近期发病率和死亡率相关,并且在其治疗方面有明确的优先事项。患者临床上可能表现为低血压、颈静脉压(JVP)升高,偶尔出现休克,且肺部清晰。右胸前导联V4R中ST段抬高≥0.1 mV是用于诊断RVI的一个易于获得的心电图征象。评估RVI的其他诊断方法包括超声心动图、放射性核素心室造影、焦磷酸锝扫描和血流动力学测量。RVI的恰当治疗包括容量负荷以维持足够的右心室前负荷、使用正性肌力药物支持以及维持房室同步。一旦出现右心室功能障碍的最早迹象,就应开始再灌注治疗。最后,大多数患者在数周至数月内完全恢复正常,这表明发生的是右心室“心肌顿抑”而非不可逆坏死。