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病灶内注射甲氨蝶呤有效治疗下唇孤立性巨大角化棘皮瘤。

Intralesional methotrexate as effective treatment in solitary giant keratoacanthoma of the lower lip.

作者信息

Spieth K, Gille J, Kaufmann R

机构信息

Department of Dermatology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.

出版信息

Dermatology. 2000;200(4):317-9. doi: 10.1159/000018395.

DOI:10.1159/000018395
PMID:10894963
Abstract

When size and location of a keratoacanthoma along with patient-related factors argue against surgical treatment, intralesional methotrexate shows to be an effective, easy and inexpensive alternative. The case report presented validates this treatment modality.

摘要

当角化棘皮瘤的大小和位置以及与患者相关的因素不支持手术治疗时，瘤内注射甲氨蝶呤被证明是一种有效、简便且廉价的替代方法。所呈现的病例报告证实了这种治疗方式。

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Intralesional methotrexate as effective treatment in solitary giant keratoacanthoma of the lower lip.病灶内注射甲氨蝶呤有效治疗下唇孤立性巨大角化棘皮瘤。
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Efficacy and Safety of Intralesional Methotrexate in the Treatment of a Large Keratoacanthoma of the Dorsal Hand in a 99-Year-Old Woman.甲氨蝶呤皮损内注射治疗一位99岁女性手部巨大角化棘皮瘤的疗效与安全性
Case Rep Dermatol. 2018 Nov 14;10(3):247-250. doi: 10.1159/000494322. eCollection 2018 Sep-Dec.
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A Giant Keratoacanthoma Treated with Surgical Excision.
经手术切除治疗的巨大角化棘皮瘤
Arch Craniofac Surg. 2015 Aug;16(2):92-95. doi: 10.7181/acfs.2015.16.2.92. Epub 2015 Aug 11.
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Treatment of keratoacanthoma: Is intralesional methotrexate an option?角化棘皮瘤的治疗：瘤内注射甲氨蝶呤是一种选择吗？
Can J Plast Surg. 2011 Summer;19(2):e15-8.
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Giant keratoacanthoma of the upper extremity treated with mohs micrographic surgery: a case report and review of current treatment modalities.采用莫氏显微外科手术治疗上肢巨大角化棘皮瘤：病例报告及当前治疗方式综述
J Clin Aesthet Dermatol. 2009 Aug;2(8):22-5.