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[某些预后因素对IB期和IIA期宫颈浸润癌综合治疗结果的影响]

[The influence of selected prognostic factors on the results of combined treatment of invasive carcinoma of the cervix on stage IB and stage IIA].

作者信息

Panek G, Kamińska G, Zieliński J

机构信息

Kliniki Nowotworów Narzadów Płciowych Kobiecych Centrum Onkologii-Instytutu im. M. Skłodowskiej-Curie w Warszawie.

出版信息

Ginekol Pol. 1999 Jul;70(7):484-9.

Abstract

This is a retrospective analysis of 180 patients treated by combination of radical surgery and radiotherapy for invasive carcinoma of the cervix in stage IB and IIA. The influence of the following prognostic factors on the survival has been evaluated: the presence of pelvic lymph node metastases, histopathology of the tumor, the size of the primary tumor, presence of vascular space invasion and surgical margines. Nodal status has proved to be the most important prognostic factor: 91% of patients without pelvic lymph node metastases survived 5 years, 57% with up to two metastases and 36% with three and more metastases to the pelvic nodes. A significantly worse prognosis has also been observed in patients with adenocarcinoma of the cervix, and with the size of the tumor of more than 2 cm.

摘要

这是一项对180例IB期和IIA期宫颈浸润癌患者行根治性手术联合放疗治疗的回顾性分析。评估了以下预后因素对生存的影响:盆腔淋巴结转移情况、肿瘤组织病理学、原发肿瘤大小、血管间隙侵犯情况及手术切缘情况。淋巴结状态已被证明是最重要的预后因素:无盆腔淋巴结转移的患者91%存活5年,有1至2个转移灶的患者57%存活5年,有3个及以上盆腔淋巴结转移的患者36%存活5年。宫颈腺癌患者以及肿瘤大小超过2 cm的患者预后也明显更差。

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