Perturbation of protein kinase C subtype activation in X-ALD fibroblasts: possible involvement of protein kinase C in the pathogenesis of adrenoleukodystrophy.

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作者信息

Ben-Yaacov A, Minichiello J, Newgreen D, Boneh A

机构信息

The Murdoch Institute, Royal Children's Hospital, Parkville, Victoria, Australia.

出版信息

J Inherit Metab Dis. 2000 Jun;23(4):416-20. doi: 10.1023/a:1005620422703.

DOI:10.1023/a:1005620422703

PMID:10896308

Abstract

摘要

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本文引用的文献

Distinct effects of fatty acids on translocation of gamma- and epsilon-subspecies of protein kinase C.脂肪酸对蛋白激酶C的γ和ε亚型易位的不同影响。

J Cell Biol. 1998 Oct 19;143(2):511-21. doi: 10.1083/jcb.143.2.511.

PKC-dependent modulation of IkB alpha-NFkB pathway in low metastatic B16F1 murine melanoma cells and in highly metastatic BL6 cells.蛋白激酶C依赖性调节低转移性B16F1小鼠黑色素瘤细胞和高转移性BL6细胞中IkBα-NFkB信号通路。

Anticancer Res. 1998 Jul-Aug;18(4A):2591-7.

Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP.X-肾上腺脑白质营养不良的治疗：极长链脂肪酸的正常化及cAMP对细胞因子诱导的抑制作用

J Lipid Res. 1998 May;39(5):1091-100.

Protein kinase C activity, phosphate uptake and endogenous substrate phosphorylation are altered in Zellweger syndrome.

J Inherit Metab Dis. 1996;19(5):661-6. doi: 10.1007/BF01799843.

Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins.小鼠角质形成细胞的分化伴随着AP-1蛋白的蛋白激酶C依赖性变化。

Oncogene. 1996 Jul 4;13(1):167-76.

Functional divergence of protein kinase C (PKC) family members. PKC gamma differs from PKC alpha and -beta II and nPKC epsilon in its competence to mediate-12-O-tetradecanoyl phorbol 13-acetate (TPA)-responsive transcriptional activation through a TPA-response element.蛋白激酶C（PKC）家族成员的功能差异。PKCγ在通过佛波酯反应元件介导12-O-十四烷酰佛波醇13-乙酸酯（TPA）反应性转录激活的能力方面，不同于PKCα、PKCβII和新PKCε。

J Biol Chem. 1993 Apr 25;268(12):9122-9.

Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.佛波醇肉豆蔻酸酯乙酸盐和地塞米松对培养的大鼠星形胶质细胞中蛋白激酶C活性和类花生酸生成的不同影响。

J Neurosci Res. 1993 Apr 15;34(6):629-34. doi: 10.1002/jnr.490340605.

Phorbol diester TPA elicits prostaglandin E release from cultured rat astrocytes.佛波酯TPA可诱导培养的大鼠星形胶质细胞释放前列腺素E。

Brain Res. 1987 Aug 11;417(2):347-9. doi: 10.1016/0006-8993(87)90461-6.

Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes.重组人恶病质素/肿瘤坏死因子而非白细胞介素-1α在转录水平下调小鼠3T3-L1脂肪细胞中脂蛋白脂肪酶基因的表达。

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