Inamura H, Tada Y, Takahashi N, Aoyagi M
Department of Otolaryngology, Yamagata University School of Medicine, Japan.
Acta Otolaryngol Suppl. 2000;542:58-61. doi: 10.1080/000164800454684.
In malignant lymphomas, especially non-Hodgkin's lymphomas, invasion to the central nervous system (CNS) often occurs. A patient is reported here with bilateral facial paralysis due to invasion of a malignant lymphoma to the CNS. Contrast magnetic resonance imaging (MRI) revealed swelling of the entire length internal auditory meatus and enhancement in the entire length of the facial nerve. Transcranial magnetic stimulation and MRI revealed that later facial nerve injury was present before the onset of paralysis due to a malignant lymphoma. Therefore treatment should be performed with consideration given to the possible invasion of the tumor to the CNS.
在恶性淋巴瘤中，尤其是非霍奇金淋巴瘤，常发生中枢神经系统（CNS）侵犯。本文报道1例因恶性淋巴瘤侵犯中枢神经系统导致双侧面瘫的患者。对比磁共振成像（MRI）显示内耳道全长肿胀，面神经全程强化。经颅磁刺激和MRI显示，在恶性淋巴瘤导致面瘫发作之前，面神经已有迟发性损伤。因此，治疗时应考虑肿瘤可能侵犯中枢神经系统。
