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[慢性疾病儿童的双能X线吸收法(DEXA)]

[Dual X-ray absorptiometry (DEXA) in children with chronic diseases].

作者信息

Feber J, Janda J, Krasnićanova H

机构信息

1st Department of Paediatrics, University Hospital Motol, Praha, Czech Republic.

出版信息

Pol Merkur Lekarski. 2000 Apr;8(46):252-3.

PMID:10897635
Abstract

Dual energy X-ray absorptiometry (DEXA) can be used for the measurement of bone density at the level of lumbar spine, whole body scan, and also for the measurement of bone mass content (BMC), lean body mass (LBM), and fat body mass (FBM). Although this method has been originally developed for the diagnosis and monitoring of osteoporosis in adults, it is used in children with chronic diseases like chronic renal failure, chronic gastrointestinal and rheumatological diseases. However, children with chronic disease often demonstrate statural growth disturbances and decreased growth velocity. Therefore, their actual height does not correspond to the actual chronological age. Normal values of DEXA for a given age are based on data from children with normal height. Interpretation of DEXA regardless of the actual height, which is usually stunted, may lead to false conclusions and wrong therapeutic attitudes. Thus, when interpreting results obtained in such patients a few transformations and calculations should be done.

摘要

双能X线吸收法(DEXA)可用于测量腰椎水平的骨密度、进行全身扫描,还可用于测量骨量(BMC)、瘦体重(LBM)和脂肪量(FBM)。尽管该方法最初是为诊断和监测成人骨质疏松症而开发的,但它也用于患有慢性疾病(如慢性肾衰竭、慢性胃肠道疾病和风湿性疾病)的儿童。然而,患有慢性疾病的儿童通常会出现身材生长障碍和生长速度下降。因此,他们的实际身高与实际年龄不相符。给定年龄的DEXA正常值是基于身高正常儿童的数据。不考虑通常发育迟缓的实际身高来解释DEXA结果,可能会导致错误的结论和错误的治疗态度。因此,在解释此类患者的检查结果时,应进行一些转换和计算。

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