化脓性链球菌SfbI蛋白与免疫球蛋白G F(ab')(2)片段的非免疫相互作用。
Nonimmune interaction of the SfbI protein of Streptococcus pyogenes with the immunoglobulin G F(ab')(2) fragment.
作者信息
Medina E, Schulze K, Chhatwal G S, Guzmán C A
机构信息
Department of Microbial Pathogenesis and Vaccine Research, Division of Microbiology, GBF-German Research Centre for Biotechnology, D-38124 Braunschweig, Germany.
出版信息
Infect Immun. 2000 Aug;68(8):4786-8. doi: 10.1128/IAI.68.8.4786-4788.2000.
Abstract
Fibronectin-binding protein I (SfbI) of Streptococcus pyogenes binds to mouse immunoglobulin G (IgG) but not to IgA or IgM in a nonimmune fashion. The fibronectin-binding domains of SfbI were responsible for this activity, which was targeted to the IgG F(ab')(2) fragment. SfbI also binds to B cells but not to CD4(+) or CD8(+) lymphocytes.
摘要
化脓性链球菌的纤连蛋白结合蛋白I（SfbI）以非免疫方式与小鼠免疫球蛋白G（IgG）结合，但不与IgA或IgM结合。SfbI的纤连蛋白结合结构域负责这种活性，该活性靶向IgG F(ab')(2)片段。SfbI也与B细胞结合，但不与CD4(+)或CD8(+)淋巴细胞结合。
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本文引用的文献
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