Kessler P, Wiltfang J, Merten H A, Neukam F W
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Friedrich-Alexander-Universität Erlangen-Nürnberg.
Mund Kiefer Gesichtschir. 2000 May;4(3):178-82. doi: 10.1007/s100060050192.
In recent years, lengthening the human mandible by distraction osteogenesis has become an accepted treatment to correct severe mandibular hypoplasia. Using intraoral unidirectional and extraoral bidirectional distraction devices we report about our experiences and results in the application of the bone distraction technique in four selected cases of syndromal disease, including various forms of mandibular hypoplastic malformations. The patients involved were a boy with Pierre Robin syndrome, a girl with unilateral facial hypoplasia in Goldenhar's syndrome, a case with Nager's syndrome, and a rare case of midline deficiency caused by partial deletion of chromosome 18 (18p-syndrome). The distraction period lasted from 6 to 30 days and new bone formation, ranging from 6 to 28 mm, was achieved.
近年来，采用牵张成骨术延长人类下颌骨已成为矫正严重下颌骨发育不全的一种公认治疗方法。我们使用口内单向和口外双向牵张装置，报告了在4例综合征性疾病（包括各种形式的下颌骨发育不全畸形）中应用骨牵张技术的经验和结果。涉及的患者包括1例患有皮埃尔·罗宾综合征的男孩、1例患有戈尔登哈综合征单侧面部发育不全的女孩、1例患有纳格尔综合征的患者以及1例因18号染色体部分缺失（18p综合征）导致的中线缺损罕见病例。牵张期持续6至30天，新骨形成达6至28毫米。
