Rollins T, Levin R M, Heymann W R
Division of Dermatology, Cooper Hospital/University Medical Center, UMDNJ-Robert Wood Johnson Medical School at Camden, Marlton, NJ 08053, USA.
J Am Acad Dermatol. 2000 Aug;43(2 Pt 2):396-9. doi: 10.1067/mjd.2000.100048.
Steatocystoma multiplex (SM) is characterized by multiple, widespread cutaneous cystic lesions. These lesions can appear virtually anywhere on the body but are more common in areas where the pilosebaceous apparatus is well developed, such as the trunk (especially the presternal area), neck, axilla, inguinal region, scalp, and proximal extremities. We present a case of a woman with predominantly acrally located SM. To the best of our knowledge, a predominantly acral distribution has never been reported. We hypothesize that this patient's phenotype may be due to her genetic predisposition, possibly involving a familial defect in keratin 17, in combination with "ectopic" acral sebaceous follicles.
多发性皮脂囊肿（SM）的特征是出现多个广泛分布的皮肤囊性病变。这些病变几乎可出现在身体的任何部位，但在皮脂腺发达的区域更为常见，如躯干（尤其是胸骨前区）、颈部、腋窝、腹股沟区、头皮和四肢近端。我们报告一例主要累及肢端的SM女性病例。据我们所知，此前从未有过主要为肢端分布的报道。我们推测，该患者的表型可能归因于其遗传易感性，可能涉及角蛋白17的家族性缺陷，再加上“异位”的肢端皮脂腺毛囊。
