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确定适合减肥治疗的患者:对美国国立心肺血液研究所肥胖教育倡议专家小组治疗建议的实证评估

Identifying patients for weight-loss treatment: an empirical evaluation of the NHLBI obesity education initiative expert panel treatment recommendations.

作者信息

Kiernan M, Winkleby M A

机构信息

Stanford Center for Research in Disease Prevention, Stanford University School of Medicine, 730 Welch Rd, Suite B, Palo Alto, CA 94304 USA.

出版信息

Arch Intern Med. 2000 Jul 24;160(14):2169-76. doi: 10.1001/archinte.160.14.2169.

Abstract

BACKGROUND

The NHLBI (National Heart, Lung, and Blood Institute) Obesity Education Initiative Expert Panel recently proposed that clinicians and other health care professionals use a new treatment algorithm to identify patients for weight-loss treatment. In addition to the usual assessment of body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters), the new algorithm includes the assessment of abdominal obesity (as measured by waist circumference) and other cardiovascular disease (CVD) risk factors.

METHODS

We examined the percentage of adults meeting the criteria of the panel's treatment algorithm: BMI > or =30 or ¿[BMI, 25.0-29.9 or waist circumference >88 cm (women) >102 cm (men)] and > or = 2 CVD risk factors¿ in a sample of 2844 black, 2754 Mexican American, and 3504 white adults, aged 25 to 64 years, from the Third National Health and Nutrition Examination Survey, 1988-1994.

RESULTS

Across ethnic groups, more than 98% of adults (normal weight, overweight, and obese) received the same treatment recommendations using the panel's algorithm and an algorithm based only on BMI and CVD risk factors, without waist circumference. For normal-weight adults, almost none (0.0%-1.8%) had a large waist circumference as defined above and 2 or more CVD risk factors. Using the usual criterion of a BMI of 30 or higher, a substantial percentage of at-risk overweight women and men (BMI, 25.0-29.9) with 2 or more CVD risk factors were missed (8.4% and 19.3%, respectively).

CONCLUSIONS

Despite the potential importance of abdominal obesity as a CVD risk factor, these results challenge the clinical utility of including waist circumference in this new algorithm and suggest that using BMI and CVD risk factors may be sufficient.

摘要

背景

美国国立心肺血液研究所(NHLBI)肥胖教育倡议专家小组最近提议,临床医生和其他医疗保健专业人员应使用一种新的治疗算法来确定适合进行减肥治疗的患者。除了常规评估体重指数(BMI,计算方法为千克体重除以米身高的平方)外,新算法还包括评估腹部肥胖(通过腰围测量)和其他心血管疾病(CVD)风险因素。

方法

我们在1988 - 1994年第三次全国健康与营养检查调查中,对年龄在25至64岁的2844名黑人、2754名墨西哥裔美国人和3504名白人成年人样本进行了检查,以确定符合该专家小组治疗算法标准的成年人百分比:BMI≥30或[BMI为25.0 - 29.9且腰围>88厘米(女性)或>102厘米(男性)]以及≥2个CVD风险因素。

结果

在所有种族群体中,超过98%的成年人(体重正常、超重和肥胖)使用该专家小组的算法和仅基于BMI及CVD风险因素而不考虑腰围的算法会得到相同的治疗建议。对于体重正常的成年人,几乎没有人(0.0% - 1.8%)具有上述定义的大腰围且有2个或更多CVD风险因素。按照BMI为30或更高的常规标准,有相当比例的有风险的超重女性和男性(BMI为25.0 - 29.9)且有2个或更多CVD风险因素被遗漏(分别为8.4%和19.3%)。

结论

尽管腹部肥胖作为CVD风险因素具有潜在重要性,但这些结果对在这种新算法中纳入腰围的临床实用性提出了挑战,并表明使用BMI和CVD风险因素可能就足够了。

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