[长期γ射线辐射暴露后心脏的生物力学功能及其肾上腺素能调节]
[The biomechanical function of the heart and its adrenergic regulation after long-term gamma radiation exposure].
作者信息
Lobanok L M, Antonenko A N
机构信息
Institute of Radiobiology, National Academy of Science of Belarus, Minsk.
出版信息
Radiats Biol Radioecol. 2000 May-Jun;40(3):245-9.
PMID:10907398
Abstract
The study of heart isolated by Langendorf's method has shown that the prolonged gamma irradiation of rats with 1.0 Gy dose (2.8 x 10(-7) Gy/sec) causes the decrease in contraction and relaxation ability, of myocardium, reduces functional response of heart to the stimulation of beta-adrenergic receptors, and increases of myocardium reaction to the stimulation of alpha-adrenergic receptors.
摘要
采用Langendorf法对离体心脏进行的研究表明，以1.0 Gy剂量（2.8×10⁻⁷ Gy/秒）对大鼠进行长时间γ射线照射，会导致心肌收缩和舒张能力下降，降低心脏对β-肾上腺素能受体刺激的功能反应，并增强心肌对α-肾上腺素能受体刺激的反应。
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