[Modification of adrenergic regulation of heart function under effect of radio-ecological factors within 10-kilometer zone of the accident at Chernobyl nuclear plant].

Rats kept within the ten-kilometer zone of Chernobyl disaster over a period of 30 days exhibited a decreased heart function response to beta-adrenoreceptor stimulus, reduced density of the receptor structures in cardiomyocytes and their affinity to specific agonists. The number of beta-adrenoreceptors in myocardium cells was restored in 6 months, but their affinity and heart function response to the effect of beta-adrenoagonists remained decreased. No significant changes were observed in regulation influenced indirectly via alpha-adrenoreceptors.