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职业性哮喘:社区样本中按性别、年龄和吸烟习惯的患病率估计

Work-related asthma: prevalence estimates by sex, age and smoking habits in a community sample.

作者信息

Bakke P S, Gulsvik A

机构信息

Department of Thoracic Medicine, University of Bergen, Norway.

出版信息

Int J Tuberc Lung Dis. 2000 Jul;4(7):649-56.

PMID:10907768
Abstract

SETTING

Two-phased study of a general population sample in Norway.

OBJECTIVE

To assess the prevalence of work-related asthma by sex, age and smoking habits.

DESIGN

The first phase, a mail questionnaire on asthma to a random sample of the general population of Hordaland County, Norway, gave a 90% response. A stratified sample of the responders (n = 1512) was invited to complete an occupational history questionnaire and performing spirometry and bronchial hyperresponsiveness. The attendance rate was 84%. Asthmatics were defined as having work-related asthma if they answered positively the questions: "Have you ever had respiratory symptoms in relation to your work? Did the symptoms improve on absence from work?"

RESULTS

The prevalence of work-related asthma was 0.9% in this population, constituting 28% of all asthmatics (95% confidence interval 25-31). The prevalence of work-related asthma was twice as high in men as in women, and did not differ significantly with age or between smoking groups.

CONCLUSION

Work-related asthma amounts to a significant proportion of total asthma in this population. This should be taken into account by health planners as it is by definition a preventable disorder.

摘要

研究背景

对挪威普通人群样本进行的两阶段研究。

研究目的

按性别、年龄和吸烟习惯评估职业性哮喘的患病率。

研究设计

第一阶段,向挪威霍达兰郡普通人群的随机样本邮寄哮喘调查问卷,回复率为90%。邀请部分回复者(n = 1512)组成分层样本,完成职业史问卷,并进行肺活量测定和支气管高反应性检测,参与率为84%。若哮喘患者对以下问题回答为“是”,则被定义为患有职业性哮喘:“你是否曾在工作时出现呼吸道症状?症状在休假时是否有所改善?”

研究结果

该人群中职业性哮喘的患病率为0.9%,占所有哮喘患者的28%(95%置信区间为25 - 31)。职业性哮喘的患病率男性是女性的两倍,在不同年龄组或吸烟组之间无显著差异。

研究结论

在该人群中,职业性哮喘在所有哮喘病例中占相当大的比例。鉴于其本质上是一种可预防的疾病,健康规划者应予以考虑。

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