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有后续淋病和衣原体感染风险的性传播疾病门诊患者:可能的“核心”传播者。

Sexually transmitted disease clinic clients at risk for subsequent gonorrhea and chlamydia infections: possible 'core' transmitters.

作者信息

Gunn R A, Fitzgerald S, Aral S O

机构信息

Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

Sex Transm Dis. 2000 Jul;27(6):343-9. doi: 10.1097/00007435-200007000-00008.

Abstract

BACKGROUND

From an sexually transmitted disease (STD) intervention perspective, developing a practical way to identify persons in core transmitter groups has been difficult. However, persons who have repeated STD infections may be in such groups.

GOAL

To evaluate a self-administered risk assessment approach that would identify STD clinic clients who were at an increased risk of being involved in gonorrhea (GC) or chlamydia (CT) transmission in the subsequent year.

STUDY DESIGN

Prospective cohort of consecutive STD clinic clients with a 1-year follow-up period.

RESULTS

During a 6-month period in 1995, 2576 STD clinic clients in San Diego completed a risk assessment. Of those clients, 204 (7.9%) had a subsequent STD and 79 (3.1%) had a subsequent GC or CT infection during the 1-year follow-up period. The strongest predictor of a subsequent GC/CT was having a recent history or current clinic visit diagnosis of GC or CT (6.1% subsequent GC/CT rate). The more past episodes of GC or CT, the higher the subsequent GC/CT rate. Unsafe sexual behavior had little effect on further increasing subsequent GC/CT risk.

CONCLUSION

STD clinic clients with a recent history of GC or CT and a high risk of subsequent GC/CT may be core transmitters who could likely benefit from risk reduction, periodic screening for GC/CT, symptom recognition counseling, and preventive treatment-the essential elements of STD-prevention case management.

摘要

背景

从性传播疾病(STD)干预的角度来看,开发一种实用的方法来识别核心传播者群体中的个体一直很困难。然而,反复感染性传播疾病的人可能属于此类群体。

目标

评估一种自我管理的风险评估方法,该方法能够识别在接下来一年中参与淋病(GC)或衣原体(CT)传播风险增加的性病门诊患者。

研究设计

对连续的性病门诊患者进行前瞻性队列研究,随访期为1年。

结果

在1995年的6个月期间,圣地亚哥的2576名性病门诊患者完成了风险评估。在这些患者中,204人(7.9%)随后感染了性传播疾病,79人(3.1%)在1年的随访期内随后感染了GC或CT。后续GC/CT感染的最强预测因素是近期有GC或CT病史或当前门诊诊断为GC或CT(后续GC/CT感染率为6.1%)。GC或CT的既往发作次数越多,后续GC/CT感染率越高。不安全的性行为对进一步增加后续GC/CT感染风险的影响很小。

结论

近期有GC或CT病史且后续GC/CT感染风险高的性病门诊患者可能是核心传播者,他们可能会从降低风险、定期筛查GC/CT、症状识别咨询和预防性治疗(性传播疾病预防病例管理的基本要素)中受益。

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