Hanai F
Inabe Orthopaedic Clinic, Inabe, Mie, Japan.
Spine (Phila Pa 1976). 2000 Aug 1;25(15):1886-92. doi: 10.1097/00007632-200008010-00005.
Changes in the electrophysiologic response of spinal dorsal horn neurons elicited by peripheral electrical stimulation were examined.
To investigate whether the electrical stimulation of peripheral nerves causes an inhibition of pain at the spinal cord level.
The wide dynamic range neurons studied were known to be excited by primary afferent fibers, not only combined A (delta) and C nociceptive fibers, but also low-threshold mechanoreceptive A (beta) fibers and A (delta) fibers of down hairs. The wide dynamic range neurons are classified as nociceptive neurons.
Responses of wide dynamic range neurons in the lumbosacral dorsal horn to input from C fibers were studied in urethane chloralose-anesthetized cats. The posterior tibial nerve and sciatic nerve were stimulated simultaneously to examine the effect on the C fiber responses elicited by superficial peroneal nerve stimulation.
Simultaneous stimulation of the posterior tibial nerve and sciatic nerve was performed with superficial peroneal nerve C fiber stimulation.
This study demonstrated that electrical stimulation of peripheral nerves leads to inhibitory input to the pain pathways at the spinal cord level.
检测外周电刺激引起的脊髓背角神经元电生理反应的变化。
研究外周神经电刺激是否在脊髓水平抑制疼痛。
所研究的广动力范围神经元已知可被初级传入纤维兴奋，不仅包括A（δ）和C伤害性纤维的组合，还包括低阈值机械感受性A（β）纤维和触须的A（δ）纤维。广动力范围神经元被归类为伤害性神经元。
在乌拉坦氯醛糖麻醉的猫中，研究腰骶部背角广动力范围神经元对C纤维输入的反应。同时刺激胫后神经和坐骨神经，以检查对腓浅神经刺激引起的C纤维反应的影响。
在腓浅神经C纤维刺激的同时，对胫后神经和坐骨神经进行了刺激。
本研究表明，外周神经电刺激在脊髓水平导致对疼痛通路的抑制性输入。
