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Activation and induction of rat liver microsomal UDP-glucuronyltransferase with 6-hydroxybenzo(a)pyrene and N-hydroxy-2-naphthylamine as substrates.

作者信息

Bock K W, Lilienblum W

出版信息

Biochem Pharmacol. 1979 Mar 1;28(5):695-700. doi: 10.1016/0006-2952(79)90161-8.

DOI:10.1016/0006-2952(79)90161-8
PMID:109090
Abstract
摘要

相似文献

1
Activation and induction of rat liver microsomal UDP-glucuronyltransferase with 6-hydroxybenzo(a)pyrene and N-hydroxy-2-naphthylamine as substrates.
Biochem Pharmacol. 1979 Mar 1;28(5):695-700. doi: 10.1016/0006-2952(79)90161-8.
2
Purification of rat-liver microsomal UDP-glucuronyltransferase. Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital.大鼠肝脏微粒体UDP-葡萄糖醛酸基转移酶的纯化。两种可被3-甲基胆蒽或苯巴比妥诱导的酶形式的分离。
Eur J Biochem. 1979 Jul;98(1):19-26. doi: 10.1111/j.1432-1033.1979.tb13155.x.
3
Determination of microsomal UDP-glucuronyltransferase in needle-biopsy specimens of human liver.人肝穿刺活检标本中微粒体UDP-葡萄糖醛酸基转移酶的测定
Eur J Clin Pharmacol. 1978 Dec 18;14(5):367-73. doi: 10.1007/BF00611908.
4
N-glucuronidation of carcinogenic aromatic amines catalyzed by rat hepatic microsomal preparations and purified rat liver uridine 5'-diphosphate-glucuronosyltransferases.大鼠肝微粒体制剂和纯化的大鼠肝脏尿苷5'-二磷酸葡萄糖醛酸基转移酶催化致癌芳香胺的N-葡萄糖醛酸化反应。
Cancer Res. 1987 Apr 15;47(8):2028-31.
5
Increase of liver microsomal benzo(a)pyrene monooxygenase activity by subsequent glucuronidation.
Naunyn Schmiedebergs Arch Pharmacol. 1978 Aug;304(1):77-9. doi: 10.1007/BF00501380.
6
Conversion of benzo[a]pyrene-3,6-quinone to quinol glucuronides with rat liver microsomes or purified NADPH-cytochrome c reductase and UDP-glucuronosyltransferase.用大鼠肝脏微粒体或纯化的NADPH-细胞色素c还原酶及UDP-葡萄糖醛酸基转移酶将苯并[a]芘-3,6-醌转化为醌葡萄糖醛酸苷。
FEBS Lett. 1980 Dec 1;121(2):269-72. doi: 10.1016/0014-5793(80)80359-0.
7
UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene.灌注大鼠肝脏和微粒体中的UDP-葡萄糖醛酸基转移酶：苯巴比妥和3-甲基胆蒽的影响
Eur J Biochem. 1974 Aug 1;46(3):451-9.
8
N-glucuronide formation of carcinogenic aromatic amines in rat and human liver microsomes.
Biochem Pharmacol. 1984 Jul 1;33(13):2041-6. doi: 10.1016/0006-2952(84)90571-9.
9
Effects of activation of UDP-glucuronyl transferase on metabolism of benzo[a]pyrene with rat liver microsomes.
J Pharmacobiodyn. 1983 Feb;6(2):105-13. doi: 10.1248/bpb1978.6.105.
10
Roles of UDP-glucuronosyltransferase in the inactivation of benzo(a)pyrene.尿苷二磷酸葡萄糖醛酸基转移酶在苯并(a)芘失活中的作用。
Adv Exp Med Biol. 1981;136 Pt A:53-73. doi: 10.1007/978-1-4757-0674-1_4.

引用本文的文献

1
Activating and inactivating reactions controlling 2-naphthylamine mutagenicity.
Arch Toxicol. 1982 Sep;50(3-4):259-66. doi: 10.1007/BF00310858.
2
Metabolism of xenobiotic compounds by enzymes in cell extracts of the fungus Cunninghamella elegans.线虫状小克银汉霉菌细胞提取物中的酶对外源化合物的代谢作用
Biochem J. 1982 Jul 1;205(1):117-22. doi: 10.1042/bj2050117.
3
Monooxygenase and UDP-glucuronyltransferase activities in established cell culture.已建立的细胞培养物中的单加氧酶和UDP-葡萄糖醛酸基转移酶活性
Arch Toxicol. 1980 Mar;44(1-3):85-97. doi: 10.1007/BF00303185.