Grøntved A M, West F
Department of Phoniatrics, Bispebjerg Hospital, Copenhagen, Denmark.
Acta Otolaryngol Suppl. 2000;543:229-31. doi: 10.1080/000164800454468.
The aim of this study was to compare oesophageal pH-metry with laryngeal signs and symptoms in patients suspected of laryngeal reflux disease. A total of 60 patients with voice disorders, who were suspected of laryngeal reflux, were tested by single probe oesophageal pH monitoring. Thirty-two suffered from reflux laryngitis. A comparison of symptoms in patients with proven reflux to patients with no reflux was made. The symptoms were more frequent in the patients in the reflux group than in the non-reflux group. There was a significant difference between the groups with regard to dysphonia, sore throat, thick mucus and heartburn. Clinical signs appeared more frequently in the reflux group than in the non-reflux group. A significant difference was found between the groups regarding oedema of the vocal cords and hyperaemia and oedema of the posterior commisure, contact granuloma, posterior wall granulation and increased muscle tension. The patients in the reflux group were given medical treatment using omeprazole, and 76% logopedic voice training program. More than 50% of the laryngeal reflux patients were treated for more than 4 months before their voice problems had resolved. It is important to realize that signs of reflux laryngitis are not confined to the posterior commisure.
本研究的目的是比较疑似喉反流疾病患者的食管pH测定结果与喉部体征和症状。共有60名疑似喉反流的嗓音障碍患者接受了单探头食管pH监测。其中32人患有反流性喉炎。对证实有反流的患者与无反流的患者的症状进行了比较。反流组患者的症状比无反流组更频繁。在发音障碍、喉咙痛、黏液增多和烧心方面，两组之间存在显著差异。临床体征在反流组比无反流组更频繁出现。在声带水肿、后联合充血和水肿、接触性肉芽肿、后壁肉芽形成以及肌肉张力增加方面，两组之间存在显著差异。反流组患者接受了奥美拉唑药物治疗，76%的患者接受了言语治疗嗓音训练计划。超过50%的喉反流患者在嗓音问题解决之前接受了超过4个月的治疗。必须认识到，反流性喉炎的体征并不局限于后联合。
