Miller T J, McGlashan T H
Yale University School of Medicine, Director, PRIME Research Center, New Haven, USA.
Conn Med. 2000 Jun;64(6):339-41.
Early detection and intervention strategies in persons who present with recently developing "prodromal" symptoms that look like early versions of the symptoms of psychosis are being investigated at a special outpatient clinic at Yale Medical School. The study aims to test whether treatment, including newer antipsychotic medication, can treat these symptoms and, in addition, might prevent or delay the onset of psychosis. Here we describe the clinic, the study, and the symptoms to look for in patients who may be at high risk for becoming psychotic in the near future. We also discuss the practical and ethical ramifications of this promising new direction in the treatment of serious mental illness.
耶鲁医学院的一家特殊门诊正在研究针对那些近期出现类似精神病早期症状的“前驱”症状患者的早期检测和干预策略。该研究旨在测试包括新型抗精神病药物在内的治疗方法是否能够治疗这些症状，此外，是否还能预防或延缓精神病的发作。在此，我们描述了该门诊、这项研究以及在近期可能有患精神病高风险的患者中需要留意的症状。我们还讨论了这一治疗严重精神疾病的有前景的新方向所带来的实际和伦理影响。
