Walker G A, Ohzawa I, Freeman R D
Group in Vision Science, School of Optometry, University of California, Berkeley 94720-2020, USA.
Vis Neurosci. 2000 May-Jun;17(3):369-79. doi: 10.1017/s0952523800173055.
The important visual stimulus parameters for a given cell are defined by the classical receptive field (CRF). However, cells are also influenced by visual stimuli presented in areas surrounding the CRF. The experiments described here were conducted to determine the incidence and nature of CRF surround influences in the primary visual cortex. From extracellular recordings in the cat's striate cortex, we find that for over half of the cells investigated (56%, 153/271), the effect of stimulation in the surround of the CRF is to suppress the neuron's activity by at least 10% compared to the response to a grating presented within the CRF alone. For the remainder of the cells, the interactions were minimal and a few were of a facilitatory nature. In this paper, we focus on the suppressive interactions. Simple and complex cell types exhibit equal incidences of surround suppression. Suppression is observed for cells in all layers, and its degree is strongly correlated between the two eyes for binocular neurons. These results show that surround suppression is a prevalent form of inhibition and may play an important role in visual processing.
对于给定细胞而言，重要的视觉刺激参数由经典感受野（CRF）定义。然而，细胞也会受到CRF周围区域呈现的视觉刺激的影响。此处描述的实验旨在确定初级视觉皮层中CRF周围影响的发生率和性质。通过对猫纹状皮层的细胞外记录，我们发现，在超过一半被研究的细胞中（56%，153/271），与仅在CRF内呈现光栅时的反应相比，CRF周围区域的刺激作用是使神经元活动至少抑制10%。对于其余细胞，相互作用极小，少数具有易化性质。在本文中，我们聚焦于抑制性相互作用。简单细胞和复杂细胞类型表现出相同的周围抑制发生率。在所有层的细胞中均观察到抑制现象，对于双眼神经元，两只眼睛之间抑制程度高度相关。这些结果表明，周围抑制是一种普遍的抑制形式，可能在视觉处理中起重要作用。
