Kaplan B S, Chassot P G, Knaack J, Morehouse D, Beaudoin J G, Guttmann R D
Can Med Assoc J. 1975 Apr 5;112(7):852-3.
Acute renal failure developed in a 55-year-old man 6 days after he had received a cadaver renal allograft. This was associated with thrombocytopenia. Extensive intraglomerular fibrin deposition was seen in a renal biopsy specimen. He was treated with corticosteroids, azathioprine, cyclophosphamide and hemodialysis with regional heparinization but not with systemic anticoagulation. This was followed by complete recovery of both renal function and histologic damage despite the fact that he did not receive anticoagulant therapy. This suggests that treatment with anticoagulants may not be necessary for all patients with intraglomerular deposits of fibrin.
一名55岁男性在接受尸体肾移植6天后发生急性肾衰竭。这与血小板减少有关。肾活检标本中可见广泛的肾小球内纤维蛋白沉积。他接受了皮质类固醇、硫唑嘌呤、环磷酰胺治疗以及局部肝素化血液透析，但未进行全身抗凝治疗。尽管他未接受抗凝治疗，但随后肾功能和组织学损伤均完全恢复。这表明并非所有有肾小球内纤维蛋白沉积的患者都需要抗凝治疗。
