Ueda N, Obana A, Miki T
Department of Ophthalmology, Osaka City University Medical School, Osaka, Japan.
Jpn J Ophthalmol. 2000 May-Jun;44(3):205-13. doi: 10.1016/s0021-5155(99)00225-7.
To determine parameters for the efficacy of transscleral cyclophotocoagulation (TSCPC) using a diode laser.
We performed TSCPC on 74 pigmented rabbits with different exposure powers and varying number of applications, followed by clinical observation and histological examination up to 24 weeks.
Based on observation of the clinical course, the most favorable parameters were 600 mW and 36 or 48 applications, which did not cause severe complications and sufficiently lowered intraocular pressure (IOP). Histological examination revealed coagulation of the epitheliums and stroma of the ciliary body at 600 mW. The stroma of the ciliary body was severely damaged at 900 mW.
Transscleral cyclophotocoagulation at 600 mW with a larger number of applications than previously reported did not cause severe complications and effected greater and more lasting lowering of IOP than TSCPC with more intense coagulation and fewer applications.
确定使用二极管激光进行经巩膜睫状体光凝术（TSCPC）的疗效参数。
我们对74只色素兔进行了不同曝光功率和不同照射次数的TSCPC，随后进行长达24周的临床观察和组织学检查。
基于临床病程观察，最适宜的参数是600毫瓦以及36次或48次照射，这不会引发严重并发症且能充分降低眼压（IOP）。组织学检查显示，600毫瓦时睫状体上皮和基质发生凝固。900毫瓦时睫状体基质受到严重损伤。
与之前报道相比，600毫瓦的经巩膜睫状体光凝术采用更多的照射次数不会引发严重并发症，并且与更强凝固作用和更少照射次数的TSCPC相比，能使眼压降低得更多且更持久。
