Back S, Dansky B S, Coffey S F, Saladin M E, Sonne S, Brady K T
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA.
Am J Addict. 2000 Winter;9(1):51-62. doi: 10.1080/10550490050172227.
This study examined the relationship between substance use, trauma history, post-traumatic stress disorder (PTSD), and psychiatric comorbidity in a treatment seeking sample of cocaine dependent individuals (N = 91). Structured clinical interviews revealed that 42.9% of the sample met DSM-III-R criteria for lifetime PTSD. Comparisons between individuals with and without lifetime PTSD revealed that individuals with PTSD had significantly higher rates of exposure to traumatic events, earlier age of first assault, more severe symptomatology, and higher rates of Axis I and Axis II diagnoses. The results illustrate a high incidence of PTSD among cocaine dependent individuals. Routine assessment of trauma history and PTSD may assist in the identification of a subgroup of cocaine users in need of special prevention and treatment efforts.
本研究调查了91名寻求治疗的可卡因依赖个体样本中物质使用、创伤史、创伤后应激障碍（PTSD）和精神共病之间的关系。结构化临床访谈显示，42.9%的样本符合DSM-III-R终身PTSD标准。有和没有终身PTSD的个体之间的比较显示，患有PTSD的个体遭受创伤事件的发生率显著更高、首次受攻击的年龄更早、症状更严重，以及轴I和轴II诊断的发生率更高。结果表明可卡因依赖个体中PTSD的发生率很高。对创伤史和PTSD进行常规评估可能有助于识别出需要特殊预防和治疗措施的可卡因使用者亚组。
