Sridharan S, Mossad S, Hoffman G
Department of Rheumatic and Immunological Diseases, The Cleveland Clinic Foundation, Ohio 44195, USA.
J Rheumatol. 2000 Jul;27(7):1792-5.
Fever, rash, and arthritis may be components of the prodrome of viral hepatitis. In the absence of jaundice and abnormal liver function tests, this form of polyarthritis is easily confused with primary autoimmune diseases. Whereas the association of systemic illness with musculoskeletal symptoms and numerous viral infections is well known, such an association with hepatitis A has only been rarely reported. We describe a case of hepatitis A infection mimicking adult onset Still's disease, and review the pathogenesis and differential diagnosis of Still's disease and the extraarticular manifestations of hepatitis.
发热、皮疹和关节炎可能是病毒性肝炎前驱期的组成部分。在没有黄疸和肝功能检查异常的情况下，这种多关节炎形式很容易与原发性自身免疫性疾病相混淆。虽然全身性疾病与肌肉骨骼症状以及众多病毒感染之间的关联已广为人知，但甲型肝炎与这种关联的报道却很少。我们描述了一例模仿成人斯蒂尔病的甲型肝炎感染病例，并回顾了斯蒂尔病的发病机制和鉴别诊断以及肝炎的关节外表现。
